STS073-743-005 Saint Louis, Missouri, U.S.A. October 1995 This color infrared photograph features metropolitan Saint Louis, the "Gateway to the West," the starting point for early explorers and settlers to the western United States. Saint Louis, the largest city in Missouri, is a great river freight handling center; a major rail center; and a wholesale, banking, financial, and industrial center. The Missouri River flows east-northeast and joins the Mississippi River north of Saint Louis, which lies south of the confluence of the Illinois and Mississippi Rivers. East of the Mississippi River and north of East Saint Louis is Horseshoe Lake. The runways of Lambert-Saint Louis International Airport are discernible northwest of downtown.